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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f22fd1e0070f48ab69cc044f2da4b88443daca9df965a537b62c96dad6bb5f' 
  AND token = 'KR8z4cEhjwup2QhXTtYKxh6pmAnkSOmxfiA9+DvAcEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}