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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de238be132b912ceaa888206f5fe2ea7a2e3d72f5dd70355b6024c2d4bf7ca9' 
  AND token = '6bsP6vNHhxVbJAY/6d56s4DENVnzWYsJ73Hz0x/Ft2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}