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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd06e7e94f76f8a726f785a4cf2fb96450afe8600108d7b6b05f05e1ef7d4fd' 
  AND token = 'xE+vlHYF7PEwseJdsw7FLpJNbHDE5JOqWNE0pSqc4Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}