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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e44ffe341c015442e1fbfd3d74f8a58f5e3962d23e2526b1dac2bb16146c90a' 
  AND token = 'Jm4T3QDP+EBjwiw/Wt3of5HnArBC/BM7LY681nL//0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}