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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3caed658d4e01779fc711e03e7fca1dfeb479ae79963901bb94560f1e85df2e3' 
  AND token = 'GuanEc9KZ+5I8YIudZ2F1YbtUpR3srttSgRSINPJRcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}