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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5730711ad7993d2afb19360fd07e8b1b4eff65c47688ecb8ba79486fa248af' 
  AND token = 'F21E/yQXl0/okn+yl4xPhvMGTL0A3VcT3t10f9xsFuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}