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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2505116723819e80e4f27da2dfc8e46a17363e2f76cf9b9bce7284d9c56700c3' 
  AND token = 'xzupxjMKTZGQ6V2PeVOXbNGTrEw6hSdeeYCLsh5SEXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}