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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437e076a5950baaf3fb3b781c4bc33ec62680bf966923f38fc6f2e982ff81444' 
  AND token = 'rH50WXheS+R4WSm5JAdgO3pDv3xsF4xJz2lWXBYQm5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}