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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ae45c1cc3180c70526dd4755170862c3ed1aa278597a59ea37d236adce9249' 
  AND token = 'FE0a4eZYTpI+yPF4Ekst2+xmYuG4Wq9oIYah15++XxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}