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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e573429be64f5601ad7a6cde9d274a1b15a25c9f66c8fb518b7e491f918109e6' 
  AND token = 'eKzdLqd3RdvgR8iXkyisuvgJ2R39Gw4iBpk3LuiwuMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}