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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9385dc49d1508ef5217055287659ea9ed016bcbb09e1b218a3459e6236fe3bd' 
  AND token = 'Ip7O6p45TEa9Fw4uQEo/NBZMzR3u7gofxqHh1hNfqXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}