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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7d5ac1c8ef139d3ffecd68f1b92c08dd02bf91ef8d47658352c3d00acf598f' 
  AND token = 'zKCSTr1xrJpv2TcGgAJHiRjPmVSBFByyOTd0jafJaMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}