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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e71a82f2b8a9feeabd08e7a010e07ec9528fe33fdcabf43c757dac9c6ce5bba' 
  AND token = '1Q/klsjXPfmjzQgliQrhm2oFofy1UmqEPM8nVG2lR1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}