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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1383d6e780e33bf8b339634dba58f543f86228d611d3f6d16552d0848cb95243' 
  AND token = 'yP+fEgukTrdZ7aTtct2gIcg/8o3lAmHOxZ02mDnG/Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}