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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a0554e6c7be9e3edf3382a4241eb44b7bb42f3f454eb016ad9022a27a6423e' 
  AND token = 'f1F+QW2eIhOFIpiQZjSSHDnMoiI8H4Nu0E2T6mHWEqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}