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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa41407a0f302a3ba2a145ebee4f656495c687722c00e396d8a038134927351' 
  AND token = 'kyJsPCTAY+lBD3t8Q+Fk+8eGBiQz8F6sX6jwavg0io4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}