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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a0f01f7d4a025f92536b44f25ed0efc305179884ad2973947adead6fdfd3319' 
  AND token = 'RXFyt3UBEYv4Z0jFvT7HOJt5rRkO2jHlbLB5MqdNym0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}