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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7353dfcb668e54dc750a6f98520a06a86a8439744b302edf3ad9c3b88156270' 
  AND token = 'MktaC00OybTchCdO/S8c4fJaBOeZPovGn2+Lj13f/00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}