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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c46804a67b89891fc7bd759262df21c4959f7f0249c99d4e5b76d41398947a' 
  AND token = 'Qi+3UJLp/YpceSURzRkwEDGx9i4k8urQBKiwryfG4G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}