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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50cb270d95af758a607d73485b2c970dd5705e56c9398acf86a547c0b0ba900' 
  AND token = 'ifm+1NxoqH9ya1qof9wfeomyZcKcT0K0NeM6hFMvzGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}