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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c4bcf75d6767a8dcb3721fb9a2eace9a048d58d80b3d0a2a84153549da5f3b6' 
  AND token = 'ns0pRxk8BzkS8Q6D+jJ2p9YnleDBKdppgDq2VRTLkUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}