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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af2fe77a1505ba4505cad3c1464c802c7a67c2a6ee959402bb0771f787a5bdf8' 
  AND token = 'C+/DmFCuU/N/7Q1EBf9fdN1P5o7lFHjx5xmgdU8VLYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}