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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f070e74fac0992b501cfc991b16a01db52d50c529e929aeb7498c951bad5de2' 
  AND token = '7rn/LM72wy6sMujclV+Wb3/841NQpMaYS3qNl7QP+mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}