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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a37d6a0d6bdbe4ad24e2a022f4ebdbba6f8b992b2798e784887aa2900f757e6' 
  AND token = '1T9v4jcBR1GhmMx1lLEWsx+gu1AfVZa69jQBZLeKe0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}