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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46974f1872a971395879d07f9ebe4a3862e655fb9df0aeaf3ad0c1678560a274' 
  AND token = 'XrBUWlCu7gR5zWI2N1LbY91bYImY3r0lzcFfk4u++9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}