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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535e4a8b3fce994aa14ea2384d8391a526237e700a81c828a2ddbe4a5aa4903c' 
  AND token = 'bboB126+9JmSe/OLVVTiKu/zp/UD7I229RLgTqC+99s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}