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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad55c0cdb114940493632d1b60a54a0a82ebf23a1650f8a9a5e8f13b2042ef00' 
  AND token = 'r1C+lO6xbxd39OUfpfvTxJZVmEHh5m8ssZEwS1wyhis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}