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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e7cbaf4ef070e5d5d75429303ccce5b87ec64692bba2f43187351720c10063' 
  AND token = 'tz3/PZ6hP+mlrVXOxfDsLvP5FGulfhjoi2Pb8EDlULM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}