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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8edfc67ce5389015a03c4ee1092d1e6ab88ed52dffa7b36efab53dfe619fa56' 
  AND token = '9G0/XXPX6jK6g02Cd6Ah8uZhaGx0ObE+FzEQSaQYsdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}