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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1eff1a0b738d90289950f028cc46204c9b3333ffe9c4555ec1a7bf82d312c1b' 
  AND token = 'PJTWXwIX6GLv5tmsj3IW2t5QUVrCXLobiA02FHvJjIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}