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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3aabae2ed21ed8ff4408dbed06d8fc1b958b5a9a500451016d4d951aca4c4dc' 
  AND token = 'gS6UQgkkCElfB2L9qg3yD2P3IeV4aEGhGgpVCS3XChI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}