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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef0e09b628edf7930c8bf7165f5f3bd951ef5e05575db241a86cbeecd6e03302' 
  AND token = 'fnHOpsLVDq6IPrPwfPoiupWLeT/SXU72Zk4wAKFrNsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}