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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f535af2ee48ada9a1a5acf894d9093486c7176519fea2b2c07c1e3c0d67a9a4' 
  AND token = 'lkRRKrJdNUfkw3yeaUSeAchv7ySzdUNet2s2653sm7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}