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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16c1a17ccc384a66abcfdb452843b62fb2a05dffff2ddfff16943b95dc4a763' 
  AND token = 'W39Vr3E8alp9Z4TGcXq1vOf9ymwCIXpuK+eD1hHCa+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}