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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '706a0cff66a15c7deaf97164910564039a460838a232cb56961c95eb9f6c476d' 
  AND token = 'bxr6I7Zzd2sY0axldGm+l7mMQGnB9B48Gts0iPdhsnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}