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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a9e0dbb1267e425b3a70e4e6a6e6acbeb84cd49ab335d75e8af398aa84cad4' 
  AND token = 'om/QL8rFBdBVYJuV8roKNKRKza/Ql8m/4bCalCrZ/wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}