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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a08d1c54284574aa657e5c1c37d8bd2feb21918cbccf2915e94c4af9ea78086f' 
  AND token = '8sTNxSH57Pm1Ay7fC0DOD3FXAyGGhtxOvEYa6fBZdRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}