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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c1c3f0584a8ae407ff44fb6ad4918928f20d5645ccc3d599d8e248f9e7bbeb5' 
  AND token = 'VIgCqCADAmOQO53Mcpn/rcOiS0aIwfyBVUh63MF0hk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}