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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946bf3566a17d195d5b64d636f28e80f8b2b9eabbb95913989d9029ce3aa3f18' 
  AND token = '1O+Of3l0kcpsizgO932kMjsJNjIJU5c8sbpyvNj0SU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}