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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e1b695808240876d7e5601ace666e671477710daf858856da1d6712ded6f87' 
  AND token = 'LGMseUYeYOlB1f0xEReZXU7uBWkYfixCog5qHUuaQ7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}