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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6433544ab6cef23ea1b2363c694e788d5c838fd72ee26f0c264233daa7b4e701' 
  AND token = '28hPORG/fushke5Qq0A3cBAtMHBvtZFBxQdW6qHQi1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}