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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66aa28aa417cc5c0b3347855568f5a4ab4f52c71d962a341718dd7af8abc3722' 
  AND token = 'oXy4uwZYLAscIwNG9f2W4I+Yg5CkmCerOVqY5otLGfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}