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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79c6d1748a6cce321f33f030aea0ee184919b69aae2e03ebfd2012be87ba290f' 
  AND token = 'w8IC9TrrYy96hGPRKINrh0SDXY0MpIdKdqSxqB1kWPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}