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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a3c032ba1dcd65e5a5690fba97c047a9cd463a2244a33ad05f058c57ccc2d13' 
  AND token = 'fBFa7uWPX4imRej3xGOhgdHYI0Mjsuk9VsjbGIF+7EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}