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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6335c896257c9f98ec6935d0f5e9c62db842f54fa6f29e6d7514733eac644454' 
  AND token = '1snuSU2wkr9TuKDjhvS3T9rgDMaZMvZUAhiNFlMHvHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}