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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc61a46d6e70921ee29e12ba8b0ea81d8db4197fb8bac16e7fd4aceb6e21b79c' 
  AND token = 'rV/tOpju3g+T0w36nuUUqokPE4ZRVROhBZ3Tey3dLzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}