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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74875b50873de31ebf54892fb2d159de9e74db1ace241c0bdfea468493dd3d5f' 
  AND token = 'JDlUzIOOsft0avUL+vHnqB67sXQ/dT6xHXAn9RHudAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}