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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e513513985c03660528163bd743c0c650a1072ae1a6a57ad9a5d17ccd5660b' 
  AND token = 'TdtYq6o7deRxDK11d0n+YPlrDUPLbByE/B3zMszArac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}