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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7751113dd7f6723ca2bfd1e9f348014cb43e2bf4e88ae47a67aef655a4cddd' 
  AND token = 'NVfL/V1Hq9BZQO+3LB1FcuCRSbFKSKePfiBcFggZeLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}