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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891acf5b2e9569dc0938edddf93c0d566b6d2a4c1bc33052e5536ceb7a6d3929' 
  AND token = 'wYg3IYHC97EB2EioYgIiO0s0WO+bbpAyhM94sdyJ9UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}